*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VT9632200
CHEMICAL NAME           : Serine, 2-(2,3,4-trihydroxybenzyl)hyrazide, DL-
CAS REGISTRY NUMBER     : 322-35-0
BEILSTEIN REFERENCE NO. : 3984490
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H15-N3-O5
MOLECULAR WEIGHT        : 257.28
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Benserazide
   * Serazide
   * DL-Serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
   * DL-Seryltrihydroxybenzylhydrazine
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 23400 mg/kg/90D-C
TOXIC EFFECTS :
   Behavioral - ataxia
   Kidney, Ureter, Bladder - other changes in urine composition
   Musculoskeletal - other changes
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   66,201,1982
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2880 mg/kg
SEX/DURATION            : female 90 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   66,201,1982
 
                            *** END OF RECORD ***