*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : VT5723000 CHEMICAL NAME : Senecionan-11,16-dione, 12-hydroxy-, and seneciphylline mixture (80:20) LAST UPDATED : 198912 DATA ITEMS CITED : 1 COMPOUND DESCRIPTOR : Reproductive Effector Natural Product SYNONYMS/TRADE NAMES : * 12-Hydroxysenecionan-11,16-dione and 13,19-didehydro-12-hydroxysenecion-11,16-dione mixture * Senecionine and seneciphylline mixture (80:20) *** HEALTH HAZARD DATA *** ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 200 mg/kg SEX/DURATION : female 1-10 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 77,461,1988 *** END OF RECORD ***