*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VT5708000
CHEMICAL NAME           : Senecionan-11,16-dione,
                          15,20-epoxy-15,20-dihydro-12-hydroxy-, hydrochloride,
                          (15-alpha,20S)-
LAST UPDATED            : 198412
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H25-N-O6.Cl-H
MOLECULAR WEIGHT        : 387.90
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * (15-alpha,20S)-15,20-Epoxy-15,20-dihydro-12-hydroxysenecionan-11,16-dione 
    hydrochloride
   * Jacobine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 138 mg/kg
TOXIC EFFECTS :
   Vascular - other changes
   Lungs, Thorax, or Respiration - chronic pulmonary edema
   Blood - hemorrhage
REFERENCE :
   FRBGAT Frontiers of Biology.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1966- Volume(issue)/page/year:
   9,142,1968
 
                            *** END OF RECORD ***