*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VT5390000
CHEMICAL NAME           : Semioxamazide, 5-hydroxy-1-(p-tolylsulfonyl)-
CAS REGISTRY NUMBER     : 62919-45-3
BEILSTEIN REFERENCE NO. : 2759155
LAST UPDATED            : 199806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H11-N3-O5-S
MOLECULAR WEIGHT        : 273.29
WISWESSER LINE NOTATION : QMVVMMSWR D1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acetic acid, (hydroxyamino)oxo-, 2-((4-methylphenyl)sulfonyl)hydrazide
   * 5-Hydroxy-1-(p-tolylsulfonyl)semioxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 11,199,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 1209 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - urine volume increased
   Blood - other changes
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 11,199,1977
 
                            *** END OF RECORD ***