*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VS3630000
CHEMICAL NAME           : 2',19'-Secovincaleukoblastine,
                          4',5'-didehydro-4'-deoxy-2',19'-dioxo
CAS REGISTRY NUMBER     : 1355-31-3
BEILSTEIN REFERENCE NO. : 0605169
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C46-H54-N4-O10
MOLECULAR WEIGHT        : 823.04
WISWESSER LINE NOTATION : T C6 B5665 2AB S BX IN QN JH&&TTTJ FO1 I1 KVO1 LOV1
                          M2 E- JT B65-11- HM PNV NU&TTJ JVO1 N2 P1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Catharine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   33GVAL "Catharanthus Alkaloids," Taylor, W.I., and N.R. Farnsworth, eds.,
   New York, Marcel Dekker, 1975  Volume(issue)/page/year: -,72,1975
 
                            *** END OF RECORD ***