*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VS3610000
CHEMICAL NAME           : 16,19-Secostrychnidine-10,16-dione,
                          21,22-dihydro-21,22-epoxy-14-hydroxy-19-methyl-
LAST UPDATED            : 199406
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H24-N2-O5
MOLECULAR WEIGHT        : 396.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   21,22-Dihydro-21,22-epoxy-14-hydroxy-19-methyl-16,19-secostrychnidine-10
     ,16-dione
   * 14-Hydroxy-21,22-alpha-epoxyicajine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APSXAS Acta Pharmaceutica Suecica.  (Apotekarsocieteten-Farmacevtiska
   Foereningen, Box 1136, S-111, 81 Stockholm, Sweden)  V.1-    1964-
   Volume(issue)/page/year: 7,329,1970
 
                            *** END OF RECORD ***