*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VS3591000
CHEMICAL NAME           : 4,8-Secosenecionan-8,11,16-trione,
                          12-(acetyloxy)-4-methyl-, (12-beta,15E)-
CAS REGISTRY NUMBER     : 60872-63-1
LAST UPDATED            : 199410
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C21-H29-N-O7
MOLECULAR WEIGHT        : 407.51
COMPOUND DESCRIPTOR     : Mutagen
                          Natural Product
SYNONYMS/TRADE NAMES :
   * O-Acetylcrotaverrine
   * (12-beta,15E)-12-(Acetyloxy)-4-methyl-4,8-secosenecionan-8,11,16-trione
   * Crotaverrine acetate
   * Ligularidine
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 68,211,1979
 
TYPE OF TEST            : Specific locus test
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTEM             : Insect - silkworm
DOSE/DURATION           : 40 ug
REFERENCE :
   KIKNAJ Kokuritsu Idengaku Kenkyusho Nenpo.  Annual Report of the National
   Institute of Genetics. (Kokuritsu Idengaku Kenkyusho, 1111 Yata, Mishima,
   Shizuoka-ken 411, Japan)  No. 1-    1949-  Volume(issue)/page/year:
   (30),70,1979
 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 2 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   45,3125,1985
 
                            *** END OF RECORD ***