*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VS2950000
CHEMICAL NAME           : 9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diol,
                          (1-alpha,3-beta,5Z,7E,22E)-
CAS REGISTRY NUMBER     : 54573-75-0
BEILSTEIN REFERENCE NO. : 4716774
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C28-H44-O2
MOLECULAR WEIGHT        : 412.72
SYNONYMS/TRADE NAMES :
   * 1-Hydroxyergocalciferol
   * 1-alpha-Hydroxyergocalciferol
   * 1-alpha-Hydroxyvitamin D2
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 178,432,1985
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 560 ug/kg/4W-I
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - changes in calcium
   Related to Chronic Data - death
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 178,432,1985
 
                            *** END OF RECORD ***