*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VQ1510000
CHEMICAL NAME           : Saponin, from Xanthocephalum microcephala
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Natural Product
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 70 mg/kg
SEX/DURATION            : female 9-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   TRBMAV Texas Reports on Biology and Medicine.  (Galveston, TX)  V.1-41(2),
   1943-81/82.  Discontinued.  Volume(issue)/page/year: 30,319,1972
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 350 mg/kg
SEX/DURATION            : female 9-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   TRBMAV Texas Reports on Biology and Medicine.  (Galveston, TX)  V.1-41(2),
   1943-81/82.  Discontinued.  Volume(issue)/page/year: 30,319,1972
 
                            *** END OF RECORD ***