*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VO5270000
CHEMICAL NAME           : Salicylic acid, 4-(3-morpholinopropionamido)-, methyl
                          ester, hydrochloride
CAS REGISTRY NUMBER     : 13065-36-6
LAST UPDATED            : 199103
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H20-N2-O5.Cl-H
MOLECULAR WEIGHT        : 344.83
WISWESSER LINE NOTATION : T6N DOTJ A2VMR CQ DVO1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Methyl 4-(3-morpholinopropionylamino)salicylate, hydrochloride
   * 4-(3-Morpholinopropionamido)salicylic acid methyl ester hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,235,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 765 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
   Behavioral - irritability
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,235,1967
 
                            *** END OF RECORD ***