*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VC8517500
CHEMICAL NAME           : 2H-Quinolizine,
                          octahydro-1-((((5-methoxy-1H-indol-3-yl)methyl)thio)m
                          ethyl)-, (1R-trans)-
CAS REGISTRY NUMBER     : 156171-05-0
LAST UPDATED            : 199512
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H28-N2-O-S
MOLECULAR WEIGHT        : 344.56
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (1R-trans)-Octahydro-1-((((5-methoxy-1H-indol-3-yl)methyl)thio)methyl)-2
     H-quinolizine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella
   Postale 227, 27100 Pavia, Italy)  V.44-   1989-  Volume(issue)/page/year:
   48,1021,1993
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella
   Postale 227, 27100 Pavia, Italy)  V.44-   1989-  Volume(issue)/page/year:
   48,1021,1993
 
                            *** END OF RECORD ***