*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VC0260000
CHEMICAL NAME           : Quinoline,
                          8-((5-(isopropylamino)pentyl)amino)-6-methoxy-,
                          phosphate
CAS REGISTRY NUMBER     : 5428-64-8
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H27-N3-O.H3-O4-P
MOLECULAR WEIGHT        : 399.48
WISWESSER LINE NOTATION : T66 BNJ HO1 JM5MY &QPQQO
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 8-(5-Isopropylamino-N-amylamino)-6-methoxyquinoline phosphate
   * 1,5-Pentanediamine, N-(6-methoxy-8-quinolinyl)-N'-(1-methylethyl)-,  
   phosphate (1:1)
   * Pentaquine monophosphate
   * Pentaquine phosphate
   * Pentaquin monophosphate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 325,7,1994
 
                            *** END OF RECORD ***