*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VB9450000
CHEMICAL NAME           : Quinoline, 4-(hydroxyamino)-6-nitro-, 1-oxide
CAS REGISTRY NUMBER     : 13442-15-4
BEILSTEIN REFERENCE NO. : 0411684
REFERENCE               : 5-22-14-00475 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H7-N3-O4
MOLECULAR WEIGHT        : 221.19
WISWESSER LINE NOTATION : T66 BNJ BO EMQ HNW
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 4-(Hydroxyamino)-6-nitroquinoline 1-oxide
   * 6-Nitro-4-hydroxylaminoquinoline 1-oxide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 60 mg/kg/I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 17,544,1969
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg/50D-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   16,631,1967
 
                            *** END OF RECORD ***