*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : VB8350000
CHEMICAL NAME : Quinoline, 2-(4-ethyl-1-piperazinyl)-4-phenyl-,
dihydrochloride
CAS REGISTRY NUMBER : 72320-60-6
LAST UPDATED : 198306
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C21-H23-N3.2Cl-H
MOLECULAR WEIGHT : 390.39
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* D 1308
* 2-(4-Ethyl-1-piperazinyl)-4-phenylquinoline dihydrochloride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 568 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - parasympatholytic
Behavioral - wakefulness
Behavioral - changes in motor activity (specific assay)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 245,283,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 119 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - parasympatholytic
Behavioral - wakefulness
Behavioral - changes in motor activity (specific assay)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 245,283,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 38 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - parasympatholytic
Behavioral - wakefulness
Behavioral - changes in motor activity (specific assay)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 245,283,1980
*** END OF RECORD ***