*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VB8325000
CHEMICAL NAME           : Quinoline, 2-ethyl-4-nitro-, N-oxide
CAS REGISTRY NUMBER     : 3741-14-8
BEILSTEIN REFERENCE NO. : 0191483
REFERENCE               : 4-20-00-03517 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C11-H10-N2-O3
MOLECULAR WEIGHT        : 218.23
WISWESSER LINE NOTATION : T66 BNJ BO C2 ENW
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 2-Ethyl-4-nitroquinoline-1-oxide
   * 4-Nitro-2-ethylquinoline-N-oxide
   * Quinoline, 2-ethyl-4-nitro-, 1-oxide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 69 mg/kg/11W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   49,33,1958
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 80 umol/L
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 31,959,1983

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***