*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VB1998000
CHEMICAL NAME           : 3-Quinolinecarboxylic acid,
                          1,4-dihydro-6,8-difluoro-1-ethyl-4-oxo-7-(1-piperazin
                          yl)-
CAS REGISTRY NUMBER     : 99726-76-8
BEILSTEIN REFERENCE NO. : 4208703
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H17-F2-N3-O3
MOLECULAR WEIGHT        : 337.36
SYNONYMS/TRADE NAMES :
   *   1,4-Dihydro-6,8-difluoro-1-ethyl-4-oxo-7-(1-piperazinyl)-3-quinolinecarb
     oxylic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1072 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 30,2163,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 193 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 30,2163,1987
 
                            *** END OF RECORD ***