*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VB1993650
CHEMICAL NAME           : 3-Quinolinecarboxylic acid,
                          1,4-dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6
                          -fluoro- 4-oxo-
CAS REGISTRY NUMBER     : 93106-60-6
BEILSTEIN REFERENCE NO. : 5307824
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C19-H22-F-N3-O3
MOLECULAR WEIGHT        : 359.44
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Baytril
   * BAY VP 2674
   * CFPQ
   *   1,4-Dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4-oxo-3-qui
     nolinecarboxylic acid
   * Enrofloxacin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und
   Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1-
   1976-  Volume(issue)/page/year: 2,87,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4336 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und
   Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1-
   1976-  Volume(issue)/page/year: 2,87,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und
   Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1-
   1976-  Volume(issue)/page/year: 2,87,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und
   Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1-
   1976-  Volume(issue)/page/year: 2,87,1987
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 60 ng/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 248,135,1991
 
                            *** END OF RECORD ***