*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VB1988000
CHEMICAL NAME           : 3-Quinolinecarboxylic acid,
                          1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-(1,1-dimethy
                          lethyl)- 6-fluoro-4-oxo-, (S)-, monomethanesulfonate,
                          dihydrate
CAS REGISTRY NUMBER     : 130548-45-7
LAST UPDATED            : 199212
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H22-F-N3-O3.C-H4-O3-S.2H2-O
MOLECULAR WEIGHT        : 479.58
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 34,29,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 188 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 34,29,1991
 
                            *** END OF RECORD ***