*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VA4146500
CHEMICAL NAME           : 4(3H)-Quinazolinone, 2-methyl-3-(2,3-xylyl)-
CAS REGISTRY NUMBER     : 1915-79-3
BEILSTEIN REFERENCE NO. : 0887483
REFERENCE               : 5-24-03-00136 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H16-N2-O
MOLECULAR WEIGHT        : 264.35
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * B 191
   * 2-Methyl-3-(2',3'-dimethylphenyl)-4-chinazolinon
   * 2-Methyl-3-(2,3-xylyl)-4(3H)-quinazolinone
   * 4(3H)-Quinazolinone, 3-(2,3-dimethylphenyl)-2-methyl-
   * Ro 353
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 13,688,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 660 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   17,616,1962
 
                            *** END OF RECORD ***