*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VA2976000
CHEMICAL NAME           : 4(3H)-Quinazolinone, 3-(p-chlorophenyl)-2-methyl-
CAS REGISTRY NUMBER     : 1788-93-8
BEILSTEIN REFERENCE NO. : 0227735
REFERENCE               : 5-24-03-00131 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H11-Cl-N2-O
MOLECULAR WEIGHT        : 270.73
WISWESSER LINE NOTATION : T66 BVN ENJ CR DG& D1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * B 127
   * 2-Methyl-3-(4-chlorophenyl)-4(3H)-quinazolinone
   * 2-Methyl-3-(4'-chlorphenyl)chinazolon-(4)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 580 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 13,688,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - muscle contraction or spasticity
   Behavioral - analgesia
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 7,626,1973
 
                            *** END OF RECORD ***