*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY8691200
CHEMICAL NAME           : 4H-Pyrrolo(2,3-g)isoquinolin-4-one,
                          1,4a,5,6,7,8,8a,9-octahydro-2,6-dimethyl-3-ethyl-,
                          hydrochloride, trans-(+-)-
CAS REGISTRY NUMBER     : 78541-98-7
LAST UPDATED            : 199409
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H22-N2-O.Cl-H
MOLECULAR WEIGHT        : 282.85
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Piquindone hydrochloride
   * Ro 22-1319
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 220 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSCHDL Psychopharmacology (Berlin).  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  V.47-    1976-
   Volume(issue)/page/year: 79,32,1983
 
                            *** END OF RECORD ***