*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VA1398000
CHEMICAL NAME           : 2,4(1H,3H)-Quinazolinedione,
                          7-chloro-1-methyl-3-(4-methyl-1-piperazinyl)-
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H17-Cl-N4-O2
MOLECULAR WEIGHT        : 308.80
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-Chloro-1-methyl-3-(4-methyl-1-piperazinyl)-2,4(1H,3H)-quinazolinedione
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 18,241,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 175 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 18,241,1983
 
                            *** END OF RECORD ***