*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VA0980000
CHEMICAL NAME           : 4-Quinazolinamine,
                          6,7-dimethoxy-2-(4-thiomorpholinyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 67958-70-7
LAST UPDATED            : 199507
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H18-N4-O2-S.Cl-H
MOLECULAR WEIGHT        : 342.88
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6,7-Dimethoxy-2-(4-thiomorpholinyl)-4-quinazolinamine monohydrochloride
   * PD 88823
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 16800 mg/kg/2W-C
TOXIC EFFECTS :
   Blood - changes in bone marrow (not otherwise specified)
   Blood - changes in other cell count (unspecified)
   Blood - changes in leukocyte (WBC) count
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   81,166,1985
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 27300 mg/kg/13W-C
TOXIC EFFECTS :
   Blood - changes in bone marrow (not otherwise specified)
   Blood - changes in other cell count (unspecified)
   Blood - changes in leukocyte (WBC) count
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   81,166,1985
 
                            *** END OF RECORD ***