*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VA0700000
CHEMICAL NAME           : Quinaldinium, 1,1'-decamethylenebis(4-amino-,
                          dichloride
CAS REGISTRY NUMBER     : 522-51-0
LAST UPDATED            : 199603
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C30-H40-N4.2Cl
MOLECULAR WEIGHT        : 527.64
WISWESSER LINE NOTATION : T66 BKJ C1 EZ B10- BT66 BKJ C1 EZ &Q 2 &G 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * BAQD 10
   * Decamethylenebis(4-aminoquinaldinium chloride)
   * 1,1'-Decamethylenebis(4-aminoquinaldinium chloride)
   * 1,10-Decamethylene-bis(4-aminoquinaldinium chloride)
   * Decamine
   * Decamine (pharmaceutical)
   * Dekadin
   * Dekamin
   * Dequadin
   * Dequadin chloride
   * Dequafungan
   * Dequalinium chloride
   * Dequavagyn
   * Dequavet
   * Efisol
   * Eriosept
   * Evazol
   * Grocreme
   * Labosept
   * Optipect
   * Phylletten
   * Polycidine
   * Sorot
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18300 ug/kg
TOXIC EFFECTS :
   Liver - fatty liver degeneration
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 82,231,1993
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 70 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 8,110,1956
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1900 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 8,110,1956
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg/15W-I
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 82,231,1993
 
                            *** END OF RECORD ***