*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UZ0850000
CHEMICAL NAME           : Pyruvic acid,
                          3-(p-((2-chloroethyl)(2-fluoroethyl)amino)phenyl)-
CAS REGISTRY NUMBER     : 4252-38-4
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H15-Cl-F-N-O3
MOLECULAR WEIGHT        : 287.74
WISWESSER LINE NOTATION : QVV1R DN2G2F
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-2-Chloroethyl-N-2-fluoroethyl-p-aminophenylpyruvic acid
   * 3-(p-((2-Chloroethyl)(2-fluoroethyl)amino)phenyl)pyruvic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD10 - Lethal Dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 14 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 8,741,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#12305
 
                            *** END OF RECORD ***