*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY4281500
CHEMICAL NAME           : Pyrrolidinium,
                          1-(3-cyclohexyl-3-hydroxy-3-phenylpropyl)-1-methyl-,
                          methyl sulfate
CAS REGISTRY NUMBER     : 6138-33-6
LAST UPDATED            : 198806
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C20-H32-N-O.C-H3-O4-S
MOLECULAR WEIGHT        : 413.63
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Compound 14045 methsulfate
   * 1-(3-Cyclohexyl-3-hydroxy-3-phenylpropyl)-1-methyl-pyrrolidinium methyl  
   sulfate
   * 1-Cyclohexyl-1-phenyl-3-pyrrolidino-1-propanol methsulfate
   * Elorine sulfate
   * Tricyclamol sulfate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 985 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 43,408,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 554 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 43,408,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15600 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 43,408,1954
 
                            *** END OF RECORD ***