*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY5767700
CHEMICAL NAME           : 2-Pyrrolidinone,
                          1-(3-(4-(diphenylmethyl)-1-piperazinyl)propyl)-5-phen
                          yl-, dihydrochloride, hydrate
CAS REGISTRY NUMBER     : 109758-22-7
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C30-H35-N3-O.2Cl-H.H2-O
MOLECULAR WEIGHT        : 543.61
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(3-(4-(Diphenylmethyl)-1-piperazinyl)propyl)-5-phenyl-2-pyrrolidinone  
   dihydrochloride H2O
   * M.G. 16166
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 42,359,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 170 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 42,359,1987
 
                            *** END OF RECORD ***