*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CB9266000
CHEMICAL NAME           : Antibiotic BBM 928B
CAS REGISTRY NUMBER     : 76149-24-1
BEILSTEIN REFERENCE NO. : 5512299
LAST UPDATED            : 199806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C62-H76-N14-O23
MOLECULAR WEIGHT        : 1385.52
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
                          Natural Product
SYNONYMS/TRADE NAMES :
   * BBM-928B
   * Luzopeptin B
   * Luzopeptin C, 2-acetate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 33,1087,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 50 ug/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,922,1986
 
                            *** END OF RECORD ***