*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CB9069500
CHEMICAL NAME           : Antibiotic 2252
CAS REGISTRY NUMBER     : 119335-99-8
LAST UPDATED            : 199206
DATA ITEMS CITED        : 4
COMPOUND DESCRIPTOR     : Natural Product
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TDKNAF Takeda Kenkyusho Nempo.  Annual Report of the Takeda Research
   Laboratories.  (Osaka, Japan) V.1-28, 1936-69.  For publisher information,
   see TAKHAA.  Volume(issue)/page/year: 13,1,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 420 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TDKNAF Takeda Kenkyusho Nempo.  Annual Report of the Takeda Research
   Laboratories.  (Osaka, Japan) V.1-28, 1936-69.  For publisher information,
   see TAKHAA.  Volume(issue)/page/year: 13,1,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TDKNAF Takeda Kenkyusho Nempo.  Annual Report of the Takeda Research
   Laboratories.  (Osaka, Japan) V.1-28, 1936-69.  For publisher information,
   see TAKHAA.  Volume(issue)/page/year: 13,1,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TDKNAF Takeda Kenkyusho Nempo.  Annual Report of the Takeda Research
   Laboratories.  (Osaka, Japan) V.1-28, 1936-69.  For publisher information,
   see TAKHAA.  Volume(issue)/page/year: 13,1,1954
 
                            *** END OF RECORD ***