*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CB1050000
CHEMICAL NAME           : 2-Anthracenesulfonic acid,
                          1-amino-9,10-dihydro-4-(m-((2-hydroxyethyl)sulfonyl)a
                          nilino- 9,10-dioxo-, hydrogen sulfate (ester),
                          disodium salt
CAS REGISTRY NUMBER     : 2580-78-1
LAST UPDATED            : 199710
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C22-H16-N2-O11-S3.2Na
MOLECULAR WEIGHT        : 626.56
WISWESSER LINE NOTATION : L C666 BV IVJ DZ ESWQ GMR CSW2OSWQ &-NA- 2
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Cavalite Brilliant Blue R
   * C.I. 61200
   * C.I. Reactive Blue 19
   * C.I. Reactive Blue 19, disodium salt
   * Reactive Blue 19
   * Remalan Brilliant Blue R
   * Remazol Brilliant Blue R
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 87 gm/kg/2Y-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Skin and Appendages - tumors
REFERENCE :
   TKORAS Trudy Kazakhskogo Nauchno-Issledovatel'skogo Instituta Onkologii i
   Radiologii.  Transactions of the Kazakh Scientific Research Institute of
   Oncology and Radiology.  (Kazakhskii Nauchno- Issledovatel'skii Institut
   Onkologii i Radiologii, Alma-Ata, USSR)  V.1-    1965-
   Volume(issue)/page/year: 3,53,1967
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 47 gm/kg/39W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Skin and Appendages - tumors
REFERENCE :
   TKORAS Trudy Kazakhskogo Nauchno-Issledovatel'skogo Instituta Onkologii i
   Radiologii.  Transactions of the Kazakh Scientific Research Institute of
   Oncology and Radiology.  (Kazakhskii Nauchno- Issledovatel'skii Institut
   Onkologii i Radiologii, Alma-Ata, USSR)  V.1-    1965-
   Volume(issue)/page/year: 3,53,1967

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - T1621
       No. of Facilities: 15 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 29 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - T1621
       No. of Facilities: 27 (estimated)
       No. of Industries: 2
       No. of Occupations: 7
       No. of Employees: 14033 (estimated)
       No. of Female Employees: 12527 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***