*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY1229100
CHEMICAL NAME           : 1-Pyrrolidineethanol,
                          2,2,5,5-tetramethyl-alpha-((o-tolyloxy)methyl)-,
                          hydrochloride, (+)-
CAS REGISTRY NUMBER     : 42373-62-6
LAST UPDATED            : 198508
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H29-N-O2.Cl-H
MOLECULAR WEIGHT        : 327.94
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (+)-Lotucaine hydrochloride
   * 2-Propanol, 1-(2-methylphenoxy)-3-(2,2,5,5-tetramethyl-1-pyrrolidinyl)-,  
   hydrochloride, (+)-
   * (+)-2,2,5,5-Tetramethyl-alpha-((o-tolyloxy)methyl)-1-pyrrolidineethanol  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1596,1973
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 8 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1596,1973
 
                            *** END OF RECORD ***