*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UX9710500
CHEMICAL NAME           : 1-Pyrrolidineethanamine,
                          beta-((2-methylpropoxy)methyl)-N-phenyl-N-(phenylmeth
                          yl)-
CAS REGISTRY NUMBER     : 64706-54-3
LAST UPDATED            : 199707
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H34-N2-O
MOLECULAR WEIGHT        : 366.60
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Bepridil
   *   beta-((2-Methylpropoxy)methyl)-N-phenyl-N-(phenylmethyl)-1-pyrrolidineet
     hanamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 180 mg/kg/30D-I
TOXIC EFFECTS :
   Cardiac - arrhythmias (including changes in conduction)
REFERENCE :
   AHJOA2 American Heart Journal.  (C.V. Mosby Co., 11830 Westline Industrial
   Dr., St. Louis, MO 63146) V.1-    1925-  Volume(issue)/page/year:
   111,1005,1986
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 90 mg/kg/3W-I
TOXIC EFFECTS :
   Cardiac - arrhythmias (including changes in conduction)
REFERENCE :
   AHJOA2 American Heart Journal.  (C.V. Mosby Co., 11830 Westline Industrial
   Dr., St. Louis, MO 63146) V.1-    1925-  Volume(issue)/page/year:
   111,1005,1986
 
                            *** END OF RECORD ***