*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY0915000
CHEMICAL NAME           : Pyrrolidine,
                          1-(2-(3-(2,2-dimethyl-7-methoxy-3-phenyl-2H-1-benzopy
                          ran-4-yl)phenoxy)ethy l)-, hydrochloride
CAS REGISTRY NUMBER     : 84394-15-0
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C30-H33-N-O3.Cl-H
MOLECULAR WEIGHT        : 492.10
WISWESSER LINE NOTATION : T66 BO CHJ C1 C1 DR& IO1 ER CO2- AT5NTJ &GH
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   *   2,2-Dimethyl-3-phenyl-4-(m-(beta-pyrrolidinoethoxy)phenyl)-7-methoxychro
     mene hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 7 mg/kg
SEX/DURATION            : female 1-7 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,592,1983
 
                            *** END OF RECORD ***