*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UX9648300
CHEMICAL NAME           : 3-Pyrrolidinamine,
                          1-(10,11-dihydrodibenzo(b,f)thiepin-10-yl)-N-ethyl-,
                          dihydrochloride, hydrate, L-(S)-
LAST UPDATED            : 198204
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H24-N2-S.2Cl-H.H2-O
MOLECULAR WEIGHT        : 414.45
WISWESSER LINE NOTATION : T C676 BS&T&J I- AT5NTJ CM2 &GH 2 &QH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * L-Dibenzo(b,f)thiepin, 10,11-dihydro-10-(3-ethylamino-1-pyrrolidinyl)-,  
   2HCl, hydrate
   * 10-(L-(S)-3-Ethylaminopyrrolidino)-10,11-dihydrodibenzo(b,f)thiepin  
   dihydrochloride hydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 155 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 17,690,1974
 
                            *** END OF RECORD ***