*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UW7525000
CHEMICAL NAME           : 4(3H)-Pyrimidinone, 2-isopropyl-6-methyl-
CAS REGISTRY NUMBER     : 2814-20-2
LAST UPDATED            : 199710
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C8-H12-N2-O
MOLECULAR WEIGHT        : 152.22
WISWESSER LINE NOTATION : T6N CNJ BY1&1 DQ F1
SYNONYMS/TRADE NAMES :
   * G 27550
   * 2-Isopropyl-4-methyl-6-hydroxypyrimidine
   * 6-Pyrimidinol, 2-isopropyl-4-methyl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAFCAU Journal of Agricultural and Food Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1953-  Volume(issue)/page/year: 18,208,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2200 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(3),69,1987
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7800 mg/kg/6W-I
TOXIC EFFECTS :
   Vascular - BP elevation not characterized in autonomic section
   Blood - changes in leukocyte (WBC) count
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - other transferases
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(3),69,1987

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***