*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UW7871330
CHEMICAL NAME           : 4H-Pyrimido(4,5-b)(1,4)thiazine-4,6(7H)-dione,
                          1,5-dihydro-2-amino-
CAS REGISTRY NUMBER     : 37489-43-3
BEILSTEIN REFERENCE NO. : 0532622
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C6-H6-N4-O2-S
MOLECULAR WEIGHT        : 198.22
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,5-Dihydro-2-amino-4H-pyrimido(4,5-b)(1,4)thiazine-4,6(7H)-dione
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 11,1205,1977
 
                            *** END OF RECORD ***