*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UW7866000
CHEMICAL NAME           : 7H-Pyrimido(4,5-b)(1,4)thiazine,
                          6-amino-4-methylthio-
CAS REGISTRY NUMBER     : 37489-30-8
BEILSTEIN REFERENCE NO. : 0524121
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C7-H8-N4-S2
MOLECULAR WEIGHT        : 212.31
WISWESSER LINE NOTATION : T66 BN DN GN JS IHJ ES1 HZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6-Amino-4-methylthio-7H-pyrimido(4,5-b)(1,4)thiazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - other oxidoreductases
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 11,1205,1977
 
                            *** END OF RECORD ***