*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UW7862000
CHEMICAL NAME           : 7H-Pyrimido(4,5-b)(1,4)thiazine,
                          6-amino-4-(dimethylamino)-
CAS REGISTRY NUMBER     : 55383-60-3
BEILSTEIN REFERENCE NO. : 0526105
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H11-N5-S
MOLECULAR WEIGHT        : 209.30
WISWESSER LINE NOTATION : T66 BN DN GN JS IHJ EN1&1 HZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6-Amino-4-(dimethylamino)-7H-pyrimido(4,5-b)(1,4)thiazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 370 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 19,567,1985
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 11,1205,1977
 
                            *** END OF RECORD ***