*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UW7861000
CHEMICAL NAME           : 7H-Pyrimido(4,5-b)(1,4)thiazine,
                          2-amino-6-(p-aminophenyl)-4-methyl-
CAS REGISTRY NUMBER     : 21576-23-8
BEILSTEIN REFERENCE NO. : 0550942
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C13-H13-N5-S
MOLECULAR WEIGHT        : 271.37
WISWESSER LINE NOTATION : T66 BN DN GN JS IHJ CZ E1 HR DZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Amino-6-(p-aminophenyl)-4-methyl-7H-pyrimido(4,5-b)(1,4)thiazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 11,1205,1977
 
                            *** END OF RECORD ***