*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UW7714000
CHEMICAL NAME           : 4H-Pyrimido(1,2-b)isoquinoline-3-carboxylic acid,
                          7,8,9,10-tetrahydro-11-cyano-10-
                          ((dimethylamino)methylene)-4-oxo-, ethyl ester
CAS REGISTRY NUMBER     : 93587-49-6
BEILSTEIN REFERENCE NO. : 5640138
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H20-N4-O3
MOLECULAR WEIGHT        : 352.43
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3-Carbethoxy-4-oxo-10-dimethylaminomethylene-11-cyanopyrimido(1,2-b)isoq
     uinoline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 18,540,1984
 
                            *** END OF RECORD ***