*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UW7681910
CHEMICAL NAME           : 5H-Pyrimido(4,5-b)(1,4)benzothiazin-9(6H)-one,
                          7,8-dihydro-7,7-dimethyl-4-(4-(2-
                          hydroxymethyl)-1-piperazinyl)-, monohydrochloride
CAS REGISTRY NUMBER     : 89513-68-8
LAST UPDATED            : 198906
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H25-N5-O2-S.Cl-H
MOLECULAR WEIGHT        : 412.00
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 480 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 17,713,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 410 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 17,713,1983
 
                            *** END OF RECORD ***