*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : UV8149600
CHEMICAL NAME : Pyrimidine, 2,4-diamino-5-(p-chlorobenzyl)-6-methyl-
CAS REGISTRY NUMBER : 7331-23-9
BEILSTEIN REFERENCE NO. : 0236954
REFERENCE : 5-25-12-00255 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C12-H13-Cl-N4
MOLECULAR WEIGHT : 248.74
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* BW 49-224
* 5-(p-Chlorobenzyl)-2,4-diamino-6-methylpyrimidine
* 2,4-Diamino-5-(p-chlorobenzyl)-6-methylpyrimidine
* 2,4-Diamino-5-(4'-chlorobenzyl)-6-methylpyrimidine
* 2,4-Pyrimidinediamine, 5-((4-chlorophenyl)methyl)-6-methyl-
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
14XBAV "International Congress of Chemotherapy, Proceedings of the 3rd
Congress, 1963," Kuemmerle, H.P., and Prezios, P., Stuttgart, Fed. Rep.
Ger., Georg Thieme Verlag, 1964 Volume(issue)/page/year: -,367,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 79 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 6,185,1951
*** END OF RECORD ***