*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV8142500
CHEMICAL NAME           : 2,4-Pyrimidinediamine,
                          5-((4-(dimethylamino)-3,5-dimethoxyphenyl)methyl)-
CAS REGISTRY NUMBER     : 56066-63-8
BEILSTEIN REFERENCE NO. : 0697192
REFERENCE               : 5-25-13-00395 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H21-N5-O2
MOLECULAR WEIGHT        : 303.41
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Aditoprim
   * 5-((4-(Dimethylamino)-3,5-dimethoxyphenyl)methyl)-2,4-pyrimidinediamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1402 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   JCHEEU Journal of Chemotherapy.  (Edizioni Riviste Scientifiche, via R.
   Giuliani, 419, 50141 Florence, Italy)  V.1-    1989-
   Volume(issue)/page/year: 5,400,1993
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JCHEEU Journal of Chemotherapy.  (Edizioni Riviste Scientifiche, via R.
   Giuliani, 419, 50141 Florence, Italy)  V.1-    1989-
   Volume(issue)/page/year: 5,400,1993
 
                            *** END OF RECORD ***