*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV8142000
CHEMICAL NAME           : 2,4-Pyrimidinediamine,
                          5-((3,4-dimethoxyphenyl)methyl)-
CAS REGISTRY NUMBER     : 5355-16-8
BEILSTEIN REFERENCE NO. : 0258464
REFERENCE               : 5-25-13-00391 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C13-H16-N4-O2
MOLECULAR WEIGHT        : 260.33
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 2,4-Diamino-5-(3,4-dimethoxybenzyl)pyrimidine
   * Diaveridin
   * Diaveridine
   * 5-((3,4-Dimethoxyphenyl)methyl)-2,4-pyrimidinediamine
   * EGIS 5645
   * Pyrimidine, 2,4-diamino-5-veratryl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3679 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PLRCAT Pharmacological Research Communications.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1969-  Volume(issue)/page/year:
   20(suppl 1),191,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6028 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PLRCAT Pharmacological Research Communications.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1969-  Volume(issue)/page/year:
   20(suppl 1),191,1988
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 261,149,1991
 
                            *** END OF RECORD ***