*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV8139711
CHEMICAL NAME           : 2,4-Pyrimidinediamine, 6-chloro-N(sup
                          4)-(2-(dimethylamino)ethyl)-N(sup 2),N(sup
                          2)-dimethyl- 5-(methylthio)-
CAS REGISTRY NUMBER     : 55416-97-2
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H20-Cl-N5-S
MOLECULAR WEIGHT        : 289.87
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-Dimethylamino-4-(2'-dimethylamino)ethylamino-5-methylthio-6-chloropyri
     midine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 525 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3968214
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 57 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3968214
 
                            *** END OF RECORD ***