*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV8139880
CHEMICAL NAME           : 2,4-Pyrimidinediamine, N(sup
                          4)-(2-(bis(1-methylethyl)amino)ethyl)-6-methoxy-N(sup
                          2)-methyl- 5-(methylthio)-N(sup 2)-phenyl-,
                          dihydrobromide
CAS REGISTRY NUMBER     : 55474-03-8
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H33-N5-O-S.2Br-H
MOLECULAR WEIGHT        : 565.49
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3968214
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3968214
 
                            *** END OF RECORD ***