*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : UV8130000
CHEMICAL NAME : Pyrimidine,
4-chloro-2-(N-methylanilino)-6-(4-methylpiperazino)-5
-methylthio-, hydrochloride
CAS REGISTRY NUMBER : 55477-31-1
BEILSTEIN REFERENCE NO. : 0897297
REFERENCE : 5-25-12-00572 (Beilstein Handbook Reference)
LAST UPDATED : 199703
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C17-H22-Cl-N5-S.Cl-H
MOLECULAR WEIGHT : 400.41
WISWESSER LINE NOTATION : T6N DNTJ A1 D- DT6N CNJ BN1&R& ES1 FG
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 4-Chloro-2-(N-methylanilino)-6-(4-methylpiperazino)-5-methylthiopyrimidi
ne hydrochloride
* 2-(N-Methyl-N-phenyl)amino-4-N-methylpiperazino-5-methylthio-6-chloropyr
imidine hydrochloride
* 2-Pyrimidinamine,
4-chloro-N-methyl-6-(4-methyl-1-piperazinyl)-5-(methylthio)-N-phenyl-, HCl
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 525 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 18,553,1975
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 112 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 18,553,1975
*** END OF RECORD ***