*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV8128000
CHEMICAL NAME           : Pyrimidine,
                          4-chloro-2-methylamino-5-methylthio-6-piperazino-
CAS REGISTRY NUMBER     : 55921-71-6
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H15-Cl-N5-S
MOLECULAR WEIGHT        : 272.81
WISWESSER LINE NOTATION : T6M DNTJ D- DT6N CNJ BM1 ES1 FG
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-Chloro-2-methylamino-5-methylthio-6-piperazinopyrimidine
   * 2-Methylamino-4-piperazino-6-chloro-5-methylthio-pyrimidine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,553,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 57 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,553,1975
 
                            *** END OF RECORD ***