*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV8112800
CHEMICAL NAME           : Pyrimidine,
                          2-((1-(5-chloro-2-methoxybenzyl)-4-piperidyl)amino)-
CAS REGISTRY NUMBER     : 76167-74-3
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H21-Cl-N4-O
MOLECULAR WEIGHT        : 332.87
WISWESSER LINE NOTATION : T6N CNJ BM- DT6NTJ A1R CG FO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-((1-(5-Chloro-2-methoxybenzyl)-4-piperidyl)amino)pyrimidine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - muscle weakness
   Vascular - relaxation (isolated tissues)
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 35,951,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - muscle weakness
   Vascular - relaxation (isolated tissues)
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 35,951,1980
 
                            *** END OF RECORD ***