*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV7900000
CHEMICAL NAME           : Pyrimidine,
                          4-chloro-2,6-bis(4-methyl-1-piperazinyl)-5-(methylthi
                          o)-, monohydrochloride
CAS REGISTRY NUMBER     : 55921-69-2
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H25-Cl-N6-S.Cl-H
MOLECULAR WEIGHT        : 393.43
WISWESSER LINE NOTATION : T6N DNTJ A1 D- BT6N CNJ DG ES1 D- AT6N DNTJ D1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bis-2,4-(N-methylpiperazino)-6-chloro-5-methylthio-pyrimidine  
   hydrochloride
   * 4-Chloro-2,6-bis(4-methyl-1-piperazinyl)-5-(methylthio)pyrimidine  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 675 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,553,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 83 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,553,1975
 
                            *** END OF RECORD ***